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Laurie E Littlepage Selected Research

triciribine

11/2020Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
12/2017The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance.
7/2012The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.

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Laurie E Littlepage Research Topics

Disease

18Neoplasms (Cancer)
01/2021 - 07/2005
13Breast Neoplasms (Breast Cancer)
10/2020 - 01/2008
4Carcinoma (Carcinomatosis)
03/2010 - 06/2005
3Neoplasm Metastasis (Metastasis)
01/2019 - 03/2010
2Triple Negative Breast Neoplasms
01/2019 - 01/2019
2Carcinogenesis
03/2010 - 06/2005
1Multiple Myeloma
11/2020
1Hypoxia (Hypoxemia)
01/2018
1Fibrosis (Cirrhosis)
01/2018
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2016
1Adenoma (Adenomas)
02/2008
1Genomic Instability
07/2005

Drug/Important Bio-Agent (IBA)

5Biomarkers (Surrogate Marker)IBA
10/2020 - 07/2012
4Pharmaceutical PreparationsIBA
11/2020 - 01/2018
4Transcription Factors (Transcription Factor)IBA
12/2017 - 07/2005
3triciribineIBA
11/2020 - 07/2012
3Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2008
3Estrogen ReceptorsIBA
01/2019 - 03/2016
3Phenobarbital (Luminal)FDA Link
01/2017 - 02/2008
2Indicators and Reagents (Reagents)IBA
12/2017 - 07/2012
2NucleosidesIBA
12/2017 - 07/2012
2EnzymesIBA
03/2010 - 07/2005
1GelsIBA
01/2021
1Conditioned Culture MediaIBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
01/2021
1LeptinIBA
01/2021
1PlasticsIBA
01/2021
1LigandsIBA
11/2020
1Glycerol (Glycerine)FDA LinkGeneric
10/2020
1LipidsIBA
10/2020
1Urea (Carbamide)FDA LinkGeneric
10/2020
1Arginine (L-Arginine)FDA Link
10/2020
1Peptides (Polypeptides)IBA
10/2020
1liposomal doxorubicin (Doxil)FDA Link
10/2020
1Glutathione (Reduced Glutathione)IBA
10/2020
1Interleukin-8B ReceptorsIBA
01/2019
11,3- bis(2- hydroxy- 5- trifluoromethylphenyl)ureaIBA
01/2019
1Recombinant ProteinsIBA
01/2019
1Potassium Channels (Potassium Channel)IBA
01/2019
1Ion Channels (Ion Channel)IBA
01/2019
1CateninsIBA
01/2019
1Discoidin Domain Receptor 1IBA
01/2018
1Paclitaxel (Taxol)FDA LinkGeneric
12/2017
1CytokinesIBA
01/2017
1Progesterone Receptors (Progesterone Receptor)IBA
03/2016
1Epidermal Growth Factor (EGF)IBA
03/2016
1NitrogenIBA
01/2016
1ChromatinIBA
06/2014
1Hormones (Hormone)IBA
06/2014
1Estrogen Receptor alphaIBA
06/2014
1Mitogen-Activated Protein KinasesIBA
07/2012
1Matrix Metalloproteinases (MMPs)IBA
03/2010
1Tumor Viral Antigens (Large T Antigen)IBA
03/2010
1AndrogensIBA
03/2010
1prinomastat (Ag3340)IBA
03/2010
1Matrix Metalloproteinase InhibitorsIBA
03/2010
1cryptdin 2IBA
03/2010
1isopeptidaseIBA
01/2008
1CarcinogensIBA
07/2005
1DNA (Deoxyribonucleic Acid)IBA
07/2005
1Matrix Metalloproteinase 3 (Stromelysin 1)IBA
07/2005
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2005
1Chemokine CXCL12IBA
06/2005
1ChemokinesIBA
06/2005

Therapy/Procedure

4Therapeutics
11/2020 - 07/2012
2Transplantation
10/2020 - 01/2016
1Bioreactors (Bioreactor)
01/2021
1Aftercare (After-Treatment)
12/2017
1Drug Therapy (Chemotherapy)
07/2012